About nondiabetic glycosuria

What is nondiabetic glycosuria?

Renal glycosuria, also known as renal glucosuria, is a rare condition in which the simple sugar glucose is eliminated (excreted) in the urine despite normal or low blood glucose levels. With normal kidney (renal) function, glucose is excreted in the urine only when there are abnormally elevated levels of glucose in the blood. However, in those with renal glycosuria, glucose is abnormally eliminated in the urine due to improper functioning of the renal tubules, which are primary components of the filtering units of the kidneys (nephrons). In most affected individuals, the condition causes no apparent symptoms (asymptomatic) or serious effects. When renal glycosuria occurs as an isolated finding with otherwise normal kidney function, the condition is thought to be inherited as an autosomal recessive trait.

What are the symptoms for nondiabetic glycosuria?

You might not know you have glycosuria until your urine is tested. Some types like renal glycosuria and gestational glycosuria don’t cause any symptoms.‌

Over time, if it’s not treated, it can cause some symptoms, including:

  • Tiredness
  • Peeing a lot
  • Feeling very thirsty
  • Weight loss
  • Feeling sick

What are the treatments for nondiabetic glycosuria?

The treatment for glycosuria depends on the cause. Diabetes is best managed with lifestyle changes and medications. 

Treatments can include:

  • Insulin
  • Metformin
  • Diet changes
  • Exercise
  • ACE inhibitors
  • Statins 
  • Anti-glucagon-like peptide-1 receptor antagonists‌

Not everyone with glycosuria is unwell or needs treatment. If you have signs of blood sugar problems, talk to your doctor. 

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